Bone Matrix Composition Following PTH Treatment is Not Dependent on Sclerostin Status
Abstract
Sclerostin and parathyroid hormones are strong negative and positive regulators of bone formation, respectively. The anabolic response induced by intermittent (iPTH) treatment is sclerostin status-dependent. However, the interaction between sclerostin and iPTH at the matrix level is unknown. The goal of the current study was to determine if iPTH treatment affects matrix composition and, if so, whether these effects are dependent on sclerostin...
Paper Details
Title
Bone Matrix Composition Following PTH Treatment is Not Dependent on Sclerostin Status
Published Date
Oct 29, 2015
Volume
98
Issue
2
Pages
149 - 157
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