The effect of solvent composition on grafting gallic acid onto chitosan via carbodiimide

The primary antioxidant (AOX) activity of chitosan can be introduced by grafting of phenolic compound – gallic acid (GA) to its amino and/or hydroxyl groups. The objective of this study was to investigate the effect of ethanol (EtOH) concentration (0%, 25%, 50%, and 75% in water) on efficiency of grafting GA onto chitosan in the presence of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC)/N-hydroxysuccinimide (NHS). The grafting was...