Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities
Abstract
Advances in molecular medicine have led to identification of worthy cellular and molecular targets located in extracellular and intracellular compartments. Effectiveness of cancer therapeutics is limited in part by inadequate delivery and transport in tumor interstitium. Parts I and II of this report give an overview on the kinetic processes in delivering therapeutics to their intended targets, the transport barriers in tumor microenvironment...
Paper Details
Title
Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities
Published Date
Feb 1, 2016
Volume
97
Pages
280 - 301
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