DISPOSITION KINETICS OF CIPROFLOXACIN AFTER DIFFERENT ORAL DOSAGE LEVEL IN RABBITS
Published: Jan 1, 2007
Abstract
Ciprofloxacin a flouroquinolone antibacterial drug was orally administered to healthy white albino rabbits (n = 12) a single dose of 10, 20, and 30 mg/Kg body weight using a randomized crossover design. Plasma samples were collected at various times over 12 hours following drug administration. The drugs were detected by high performance liquid chromatography (HPLC), and plasma drug concentration versus time curve were subjected to...
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