Effect of Sesbania grandiflora and Sesbania sesban bark on carrageenan induced acute inflammation and adjuvant-induced arthritis in rats.

Nitric Oxide (NO) can autoregulate its own formation by feedback inhibition of the inducible Nitric Oxide Synthase (iNOS). Modulation of biosynthesis or activity of NO results in amelioration if pathogenesis of experimental arthritis. However, little is known about feedback mechanism on NO generation in response to carrageenan induced paw oedema and adjuvant- induced arthritis. In the present study we have examined the effects of prophylactic...