Hepatic flares induced by disease-modifying treatments in patients with multiple sclerosis

Introduction Multiple sclerosis is a chronic inflammatory disease of the central nervous system of autoimmune origin. During the last decades, several disease-modifying therapies have been licensed that ameliorate the course of the disease. The purpose of these DMT is to reduce inflammation, disease activity, as measured by MRI and relapse rate. However, DMT and interferons, in particular, are associated with a number of adverse reactions which...