FORMULATION DEVELOPMENT EX-VIVO AND IN-VIVO EVALUATION OF NANOEMULSION FOR TRANSDERMAL DELIVERY OF GLIBENCLAMIDE
Published: Jan 1, 2013
Abstract
Introduction: Transdermal administration of glibenclamide (GLBD) might offer some advantages over oral route in subject with the treatment of hyperglycemia in non-insulin dependent diabetes mellitus (NIDDM). Objective: The objective of the present study was to develop the nanoemulsion gel for transdermal delivery of glibenclamide (GLBD) and to evaluate with respect to various Ex-vivo and in-vivo parameters. Nanoemulsions do not need the chemical...
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