The population genetics of drug resistance evolution in natural populations of viral, bacterial and eukaryotic pathogens

Volume: 25, Issue: 1, Pages: 42 - 66
Published: Dec 17, 2015
Abstract
Drug resistance is a costly consequence of pathogen evolution and a major concern in public health. In this review, we show how population genetics can be used to study the evolution of drug resistance and also how drug resistance evolution is informative as an evolutionary model system. We highlight five examples from diverse organisms with particular focus on: (i) identifying drug resistance loci in the malaria parasite Plasmodium falciparum...
Paper Details
Title
The population genetics of drug resistance evolution in natural populations of viral, bacterial and eukaryotic pathogens
Published Date
Dec 17, 2015
Volume
25
Issue
1
Pages
42 - 66
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