DNA Editing by APOBECs: A Genomic Preserver and Transformer.
Abstract
Information warfare is not limited to the cyber world because it is waged within our cells as well. The unique AID (activation-induced cytidine deaminase)/APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide) family comprises proteins that alter DNA sequences by converting deoxycytidines to deoxyuridines through deamination. This C-to-U DNA editing enables them to inhibit parasitic viruses and retrotransposons by disrupting their...
Paper Details
Title
DNA Editing by APOBECs: A Genomic Preserver and Transformer.
Published Date
Jan 1, 2016
Journal
Volume
32
Issue
1
Pages
16 - 28
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