Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes
Abstract
Determining the full complement of protein-coding genes is a key goal of genome annotation. The most powerful approach for confirming protein-coding potential is the detection of cellular protein expression through peptide mass spectrometry (MS) experiments. Here, we mapped peptides detected in seven large-scale proteomics studies to almost 60% of the protein-coding genes in the GENCODE annotation of the human genome. We found a strong...
Paper Details
Title
Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes
Published Date
Jun 16, 2014
Journal
Volume
23
Issue
22
Pages
5866 - 5878
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