The molecular genetics of Marfan syndrome and related disorders

Volume: 43, Issue: 10, Pages: 769 - 787
Published: Oct 1, 2006
Abstract
Marfan syndrome (MFS), a relatively common autosomal dominant hereditary disorder of connective tissue with prominent manifestations in the skeletal, ocular, and cardiovascular systems, is caused by mutations in the gene for fibrillin-1 (FBN1). The leading cause of premature death in untreated individuals with MFS is acute aortic dissection, which often follows a period of progressive dilatation of the ascending aorta. Recent research on the...
Paper Details
Title
The molecular genetics of Marfan syndrome and related disorders
Published Date
Oct 1, 2006
Volume
43
Issue
10
Pages
769 - 787
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.