Role of Anti-Oxidants in Atherosclerosis: Epidemiological and Clinical Update
Abstract
Low density lipoprotein (LDL) oxidative modification in the vascular wall seems to be a key factor in atherosclerosis development. Oxidised LDLs might recruit monocytes and favour their transformation into foam cells through a receptor-mediated intake (scavenger pathway). Moreover oxidised LDLs show cytotoxic potential which is probably responsible for endothelial cell damage and macrophage degeneration in the atherosclerotic human plaque....
Paper Details
Title
Role of Anti-Oxidants in Atherosclerosis: Epidemiological and Clinical Update
Published Date
Jun 1, 2005
Volume
11
Issue
16
Pages
2017 - 2032
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