Comment on: Efficacy and safety of tigecycline: a systematic review and meta-analysis

published a systematic review andmeta-analysis of 15 randomized clinical trials (RCTs) that com-pared tigecycline with other antibiotics for the treatment ofsevere infections. The overall 30 day mortality was estimatedto be higher with tigecycline compared with other regimens[relative risk (RR) 1.29, 95% confidence interval (CI) 1.02–1.64];therefore, the authors recommend that clinicians should avoidtigecycline monotherapy in the treatment of...