Characterization of a Unique ClpB Protein of Mycoplasma pneumoniae and Its Impact on Growth

Mycoplasma pneumoniae accounts for 20 to 30% of all community-acquired pneumonia and has been associated with other airway pathologies, including asthma, and a range of extrapulmonary manifestations. Although the entire genomic sequence of M. pneumoniae has been completed, the functions of many of these genes in mycoplasma physiology are unknown. In this study, we focused on clpB , a well-known heat shock gene in other bacteria, to examine its...