• References (47)
  • Citations (1)
Published on May 1, 1983in American Journal of Psychiatry 13.40
Dwight L. Evans50
Estimated H-index: 50
(University of North Carolina at Chapel Hill),
Gordon B. Burnett7
Estimated H-index: 7
(University of North Carolina at Chapel Hill),
C. B. Nemeroff42
Estimated H-index: 42
(University of North Carolina at Chapel Hill)
81 Citations Source Cite
Published on May 1, 2006in Movement Disorders 8.32
Martine Visser23
Estimated H-index: 23
(Leiden University Medical Center),
Albert F.G. Leentjens37
Estimated H-index: 37
(Maastricht University)
+ 2 AuthorsJacobus J. van Hilten54
Estimated H-index: 54
(Leiden University Medical Center)
We evaluated the validity, reliability, and potential responsiveness of the Beck Depression Inventory (BDI) in patients with Parkinson's disease (PD). In part 1 of the study, 92 patients with PD underwent a structured clinical interview for DSM major depression and based on this patients were considered depressed (PD-D) or nondepressed (PD-ND). Subsequently, patients filled in the BDI. In part 2, a postal survey consisting the BDI was performed in 185 PD patients and 112 controls. Test–retest re...
133 Citations Source Cite
Published on Nov 1, 2002in Comprehensive Psychiatry 2.13
Stewart A. Shankman23
Estimated H-index: 23
(Stony Brook University),
Daniel N. Klein71
Estimated H-index: 71
(Stony Brook University)
Abstract It has long been debated whether depression is best classified with a categorical or dimensional diagnostic system. There has been surprisingly little discussion, however, of what the contents of a dimensional classification should include, with most studies employing a single dimension based on symptom severity. The present study explored whether a dimension based on prior course of depression increases the validity of a dimensional model based on symptom severity alone and whether the...
17 Citations Source Cite
Published on Dec 1, 1996in Neuroscience Letters 2.16
Gennady N. Smagin15
Estimated H-index: 15
(Louisiana State University),
Ruth Babette Harris40
Estimated H-index: 40
(Louisiana State University),
Donna H. Ryan21
Estimated H-index: 21
(Louisiana State University)
Abstract It has been proposed that corticotropin-releasing factor (CRF) released during stress in the region of the locus coeruleus (LC) induces changes in behavior that are typical indices of anxiety. The experiments tested the ability of a CRF antagonist, αhCRF 9–41 , to attenuate stress-induced defensive withdrawal in rats. 1 μg of αhCRF in 300 nl was infused bilaterally in the LC of rats 10 min prior to 30 min immobilization. The apparatus consisted of a small chamber set on one side of a 1 ...
56 Citations Source Cite
Published on Oct 1, 2006in Amino Acids 2.91
M. E. Keck1
Estimated H-index: 1
Affective disorders tend to be chronic and life-threatening diseases: suicide is estimated to be the cause of death in 10–15% of individuals with major depressive disorders. Major depression is one of the most prevalent and costly brain diseases with up to 20% of the worldwide population suffering from moderate to severe forms of the disease. Only 50% of individuals with depression show full remission in response to currently available antidepressant drug therapies which are based on serendipito...
71 Citations Source Cite
Published on Jan 1, 2005in Psychological Assessment 3.37
Thomas E. Joiner89
Estimated H-index: 89
(Florida State University),
Rheeda L. Walker18
Estimated H-index: 18
(University of South Carolina)
+ 2 AuthorsKelly C. Cukrowicz28
Estimated H-index: 28
(Florida State University)
From diverse perspectives, there is little doubt that depressive symptoms cohere to form a valid and distinct syndrome. Research indicates that an evidence-based assessment of depression would include (a) measures with adequate psychometric properties; (b) adequate coverage of symptoms; (c) adequate coverage of depressed mood, anhedonia, and suicidality; (d) an approach to suicidality that distinguishes between resolved plans and preparations and desire and ideation; (e) assessment of the atypic...
110 Citations Source Cite
Published on Jan 1, 2003in Brain Research 3.13
Earl Thomas11
Estimated H-index: 11
(Bryn Mawr College),
Luise Pernar5
Estimated H-index: 5
(Bryn Mawr College)
+ 1 AuthorsRita J. Valentino67
Estimated H-index: 67
(Children's Hospital of Philadelphia)
Abstract Corticotropin-releasing factor (CRF) has substantial effects on brain serotonergic activity, especially in limbic structures related to stress and anxiety. For example, relatively low doses of CRF administered into the dorsal raphe nucleus (DRN) decrease DRN unit activity and serotonin release in the lateral septum (LS), a limbic target of the DRN. In contrast, higher doses of CRF tend to be excitatory on both endpoints. The present experiment sought to establish the functional connecti...
43 Citations Source Cite
Published on Aug 1, 1992in Brain Research 3.13
Artur H. Swiergiel3
Estimated H-index: 3
(University of Wisconsin-Madison),
Lorey K. Takahashi25
Estimated H-index: 25
(University of Wisconsin-Madison)
+ 1 AuthorsNed H. Kalin62
Estimated H-index: 62
(University of Wisconsin-Madison)
Abstract Intracerebroventricularly administered α-helical CRF 9−41 , a corticotropin-releasing factor (CRF) receptor antagonist, is known to reduce a variety of stress-induced behavioral responses. This study examined in rats whether antagonism of CRF receptors in the region of locus coeruleus (LC) plays a role in reducing freezing induced by electric foot shock. Freezing is a well-characterized defensive response to stress and has been demonstrated to index an animal's degree of fear. A CRF-rec...
72 Citations Source Cite
Published on Feb 1, 2008in Biological Psychiatry 11.98
Christine Heim54
Estimated H-index: 54
(Emory University),
Tanja Mletzko10
Estimated H-index: 10
(Emory University)
+ 2 AuthorsCharles B. Nemeroff128
Estimated H-index: 128
(Emory University)
Background The dexamethasone/corticotropin-releasing factor (CRF) test is considered to be the most sensitive measure of hypothalamic–pituitary–adrenal (HPA) axis hyperactivity and has been demonstrated to be altered in patients with major depression (MDD). Although childhood trauma is a demonstrated risk factor for MDD and patients with a history of childhood abuse and MDD demonstrate HPA axis hyperactivity, the dexamethasone/CRF test remains unstudied in this population. We determined the impa...
239 Citations Source Cite
Published on Jan 1, 2001in Health Psychology 3.18
Randolph C. Arnau17
Estimated H-index: 17
(Texas A&M University),
Mary W. Meagher27
Estimated H-index: 27
(Texas A&M University)
+ 1 AuthorsRachel Bramson11
Estimated H-index: 11
(Texas A&M University)
Abstract This study evaluated the psychometric characteristics of the Beck Depression Inventory-II (BDI-II; A. T. Beck, R. A. Steer, & G. K. Brown, 1996) in a primary care medical setting. A principal-components analysis with Promax rotation indicated the presence of 2 correlated factors, Somatic-Affective and Cognitive, which explained 53.5% of the variance. A hierarchical, second-order analysis indicated that all items tap into a second-order construct of depression. Evidence for convergent va...
471 Citations Source Cite
Cited By1
Published on Nov 1, 2010in Developmental Psychobiology 2.49
Aniko Korosi5
Estimated H-index: 5
(University of California, Irvine),
Tallie Z. Baram68
Estimated H-index: 68
(University of California, Irvine)
The concept that early-life experience influences the brain long-term has been extensively studied over the past 50 years, whereas genetic factors determine the sequence and levels of expression of specific neuronal genes, this genetic program can be modified enduringly as a result of experience taking place during critical developmental periods. This programming is of major importance because it appears to govern many behavioral and physiological phenotypes and promote susceptibility or resilie...
47 Citations Source Cite