Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men.
Abstract
Insulin action and obesity are both correlated with the density of muscle capillary supply in humans. Since the altered muscle anatomy in the obese might affect interstitial insulin concentrations and reduce insulin action, we have cannulated peripheral lymphatic vessels in lean and obese males, and compared peripheral lymph insulin concentrations with whole body glucose uptake during a euglycemic, hyperinsulinemic clamp. Lymph insulin...
Paper Details
Title
Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men.
Published Date
Jan 1, 1994
Volume
93
Issue
1
Pages
10 - 16
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