How the case against the MMR vaccine was fixed.

Published on Jan 5, 2011in BMJ27.60
· DOI :10.1136/bmj.c5347
Brian Deer7
Estimated H-index: 7
In the first part of a special BMJ series, Brian Deer exposes the bogus data behind claims that launched a worldwide scare over the measles, mumps, and rubella vaccine, and reveals how the appearance of a link with autism was manufactured at a London medical school
  • References (14)
  • Citations (141)
Published on Jan 1, 2012
Deborah Hirtz45
Estimated H-index: 45
Ann Wagner13
Estimated H-index: 13
+ 1 AuthorsElliott H. Sherr1
Estimated H-index: 1
Published on Jan 1, 2011in British Journal of Psychiatry7.23
Cees Boerhout4
Estimated H-index: 4
J. T. van Busschbach15
Estimated H-index: 15
+ 1 AuthorsDiederik S. Wiersma64
Estimated H-index: 64
Once upon a time the depressed were idle, the psychotic were possessed, and those suffering with any form of mental illness were punished, exorcised, ridiculed, confined, excluded or criminalised. Thankfully, as a result of investment in research, there have been significant advances in the understanding of the brain and the biological underpinnings of mental disorders, emotions and behaviours, including aggression. To advocate the omission of the scientific study of aggression from that of the ...
Published on Apr 15, 2010in BMJ27.60
Brian Deer7
Estimated H-index: 7
Andrew Wakefield’s claims for a new bowel condition in autistic children have been largely overlooked in the furore over MMR vaccination. Brian Deer reports
Published on Jan 1, 2010in Pediatrics5.40
Timothy Buie17
Estimated H-index: 17
(Harvard University),
Daniel B. Campbell25
Estimated H-index: 25
(SC: University of Southern California)
+ 24 AuthorsArthur L. Beaudet94
Estimated H-index: 94
(BCM: Baylor College of Medicine)
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary pa...
Published on Nov 1, 2004in The Journal of Pediatrics3.74
Sami Turunen1
Estimated H-index: 1
(University of Oulu),
Tuomo J. Karttunen41
Estimated H-index: 41
(University of Oulu),
Jorma Kokkonen29
Estimated H-index: 29
(University of Oulu)
Objective To investigate the incidence of cow's milk allergy as evidenced by milk challenge and the findings of endoscopic and immunohistochemical examinations in children with chronic and refractory constipation. Study design Thirty-five study subjects (mean age, 8.3 ± 3.3 years; range, 3-15 years; 17 girls) and 15 control subjects (mean age, 11.7 ± 3.2 years; range, 2-15 years; 9 girls) were studied by colonoscopy and a 4-week cow's milk elimination and challenge. Results Lymphoid nodular hype...
Published on Mar 1, 2004in The Lancet59.10
Simon Murch30
Estimated H-index: 30
Andrew Anthony9
Estimated H-index: 9
+ 7 AuthorsJohn A. Walker-Smith25
Estimated H-index: 25
This statement refers to the Early Report “Ileal-lymphoidnodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children”, published in The Lancet in 1998. It is made by 10 of the 12 original authors who could be contacted. It should be noted that this statement does not necessarily reflect the views of the other co-authors. The main thrust of this paper was the first description of an unexpected intestinal lesion in the children reported. Further evidence has been fo...
Published on Oct 1, 2003in Pediatrics5.40
Nadeem A. Afzal19
Estimated H-index: 19
Simon H. Murch24
Estimated H-index: 24
+ 3 AuthorsRobert Heuschkel16
Estimated H-index: 16
Objective. Recent evidence suggests that autistic children may have significant gastrointestinal symptoms. Although constipation occurs in 2% to 5% of healthy children, its clinical diagnosis is often difficult in children with behavioral disorders. We thus aimed to assess the prevalence of fecal loading in autistic children with gastrointestinal symptoms and to identify possible predictors of constipation. Methods. We studied abdominal radiographs of 103 autistic children (87 boys) who were ref...
Published on Feb 1, 1998in The Lancet59.10
Aj Wakefield25
Estimated H-index: 25
(Royal Free Hospital),
Simon H. Murch24
Estimated H-index: 24
(Royal Free Hospital)
+ 10 AuthorsPeter Harvey5
Estimated H-index: 5
(Royal Free Hospital)
Summary Background We investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder. Methods 12 children (mean age 6 years [range 3–10], 11 boys) were referred to a paediatric gastroenterology unit with a history of normal development followed by loss of acquired skills, including language, together with diarrhoea and abdominal pain. Children underwent gastroenterological, neurological, and developmental assessment and review of developmental reco...
Published on Sep 15, 1999
Kenneth F. Swaiman20
Estimated H-index: 20
Stephen Ashwal14
Estimated H-index: 14
In two volumes, this book addresses the range of neurological diseases that can occur from birth to adolescence. All the information has been updated and revised with new chapters on epilepticus, mitochondrial encephalomyelopathies and peroxisomal disorders.
Cited By141
Published on Jan 1, 2020
Josephine Adekola (GCU: Glasgow Caledonian University)
This chapter begins by re-highlighting the weaknesses in existing conceptualisations of the social amplification of risk framework and then provides a detailed account of social amplification of risk from the power and expertise perspectives. The account of the social amplification of risk framework provided here is based on insight from the literature (see Chaps. 1, 2 and 3). The account presented in this chapter focuses less on the ‘who’ factors used in the existing conceptualisation of the so...
Published on Jan 1, 2020
Josephine Adekola (GCU: Glasgow Caledonian University)
This chapter is the second results chapter of this book. It examines the measles, mumps and rubella debate (between 1998 and 2003) and assesses evidence on how power and expertise, as well as communication and trust, might shape risk communication about public health and safety in a policy context. This case study particularly evidences how technical expertise and experiential expertise shape public health communication and associated policymaking. It also highlights the bias against experientia...
Published on Sep 11, 2019in Frontiers for Young Minds
Emma Slack26
Estimated H-index: 26
Markus Arnoldini9
Estimated H-index: 9
+ 12 AuthorsNicole Howald
Published on Nov 17, 2017in Health Informatics Journal2.30
Michael Deiner7
Estimated H-index: 7
Cherie Fathy1
Estimated H-index: 1
+ 6 AuthorsTravis C. Porco39
Estimated H-index: 39
Social media posts regarding measles vaccination were classified as pro-vaccination, expressing vaccine hesitancy, uncertain, or irrelevant. Spearman correlations with Centers for Disease Control and Prevention–reported measles cases and differenced smoothed cumulative case counts over this period were reported (using time series bootstrap confidence intervals). A total of 58,078 Facebook posts and 82,993 tweets were identified from 4 January 2009 to 27 August 2016. Pro-vaccination posts were co...
Published on Aug 21, 2019
Tara C. Smith22
Estimated H-index: 22
(KSU: Kent State University),
Maimuna S. Majumder1
Estimated H-index: 1
(Harvard University)
Published on Jun 1, 2019in Journal of Theoretical Biology1.88
Aniruddha Deka (Shiv Nadar University), Samit Bhattacharyya9
Estimated H-index: 9
(Shiv Nadar University)
Abstract Communicable diseases are leading cause of child mortality in developing and under-developed countries. Public health ministries in states and country allocate a considerable amount of budget every year for vaccination campaigns to control infections. Even third-party agencies such as Gates Foundation, UNDP, GAVI, World Bank, WHO also allocate huge funds to under-developed and developing countries for vaccination programs and disease eliminations. However, economic constraints and curre...
Published on Apr 1, 2019in Cellular and Molecular Life Sciences7.01
Sven Bölte42
Estimated H-index: 42
(Stockholm County Council),
Sonya Girdler19
Estimated H-index: 19
(Curtin University),
Peter B. Marschik25
Estimated H-index: 25
(Stockholm County Council)
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous etiology. While it is widely recognized that genetic and environmental factors and their interactions contribute to autism phenotypes, their precise causal mechanisms remain poorly understood. This article reviews our current understanding of environmental risk factors of ASD and their presumed adverse physiological mechanisms. It comprehensively maps the significance of parental age, teratogenic compounds, perinat...
Published on Mar 15, 2019in Western Journal of Communication
Brett Jacob Bricker3
Estimated H-index: 3
(KU: University of Kansas),
Jacob William Justice1
Estimated H-index: 1
(KU: University of Kansas)
This essay analyzes the arguments of the antivaccination movement, arguing that many analysts have misdiagnosed the root causes of vaccine skepticism. It is no longer productive for argumentation scholars to discount scientific skepticism as simply a problem of an ignorant public, religious zealots, or conservative ideologies, because antivaccine beliefs transcend ideology. The authors argue that simplistic accusations of blame on one political or cultural subgroup are inaccurate, and that the e...
Published on Dec 6, 2018in Frontiers of Medicine in China
Suzan Dijkstra (UU: Utrecht University), Gautam Kok1
Estimated H-index: 1
(UU: Utrecht University)
+ 2 AuthorsRemi Stevelink2
Estimated H-index: 2
(UU: Utrecht University)
We live in an age where the sharing of scientific findings and ideas is no longer confined to people with access to academic libraries or scientific journals. Social media have permitted for knowledge and ideas to be shared with an unprecedented speed and magnitude. This has made it possible for research findings to have a greater impact and to be rapidly implemented in society. However, the spread of unfiltered, unreferenced and non-peer-reviewed articles through social media comes with dangers...