Sex-Specific Association between Estrogen Receptor-α Gene Variation and Measures of Adiposity: The Framingham Heart Study

Volume: 90, Issue: 11, Pages: 6257 - 6262
Published: Nov 1, 2005
Abstract
Polymorphisms in estrogen receptor-alpha (ESR1) may be associated with variation in body mass index and waist circumference. However, most prior studies have been limited by sample size and power.DNA from 1763 unrelated men and women (mean age, 56 yr) from the Framingham Heart Study offspring cohort was genotyped for four ESR1 polymorphisms: T30C (rs2077647) in exon 1, PvuII (rs2234693), and XbaI (rs 9340799) in intron 1, and C1335G (rs 1801132)...
Paper Details
Title
Sex-Specific Association between Estrogen Receptor-α Gene Variation and Measures of Adiposity: The Framingham Heart Study
Published Date
Nov 1, 2005
Volume
90
Issue
11
Pages
6257 - 6262
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