Review paper
Procollagen trafficking, processing and fibrillogenesis
Abstract
Collagen fibrils in the extracellular matrix allow connective tissues such as tendon, skin and bone to withstand tensile forces. The fibrils are indeterminate in length, insoluble and form elaborate three-dimensional arrays that extend over numerous cell lengths. Studies of the molecular basis of collagen fibrillogenesis have provided insight into the trafficking of procollagen (the precursor of collagen) through the cellular secretory pathway,...
Paper Details
Title
Procollagen trafficking, processing and fibrillogenesis
Published Date
Apr 1, 2005
Journal
Volume
118
Issue
7
Pages
1341 - 1353
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Notes
History