Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for primary central nervous system lymphoma
Abstract
Primary central nervous system lymphomas (PCNSLs) are highly aggressive tumors. Chemotherapy has improved prognosis significantly; however, early diagnosis is crucial for effective treatment. Presently, the diagnosis of PCNSL depends on histopathology of tumor biopsies. We have previously demonstrated differential expression of microRNAs in cerebrospinal fluid (CSF) samples from patients with PCNSL. Based on promising findings about circulating...
Paper Details
Title
Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for primary central nervous system lymphoma
Published Date
Aug 6, 2015
Journal
Volume
18
Issue
3
Pages
361 - 367
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