Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia
Abstract
Sixteen hyperlipidemic men were enrolled in a randomized, placebo-controlled, double-blind, cross-over study to evaluate the effect of ezetimibe 10 mg and simvastatin 40 mg, coadministered and alone, on the in vivo kinetics of apolipoprotein (apo) B-48 and B-100 in humans. Subjects underwent a primed-constant infusion of a stable isotope in the fed state. The coadministration of simvastatin and ezetimibe significantly reduced plasma...
Paper Details
Title
Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia
Published Date
Jul 1, 2009
Journal
Volume
50
Issue
7
Pages
1463 - 1471
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