Neuroprotective effect of Spirulina (Arthrospira) maxima against kainic acid-induced neurotoxicity

Oxidative stress has been implicated in the pathophysiology of neurologic disorders and brain dysfunctions. Spirulina (Arthrospira) maxima (SP) is a cyanobacteria with nutritional, pharmacological and important antioxidant activity. This study aims to evaluate the neuroprotective role of SP against kainic acid (KA) neurotoxicity. Male SW mice were treated with SP for 24 days (200, 400 and 800 mg/kg, (o.v.) and KA (35 mg/kg) was intraperitoneally...