Determination of Molecular Markers for BRCA1 and BRCA2 Heterozygosity Using Gene Expression Profiling
Abstract
Approximately 5% of all breast cancers can be attributed to an inherited mutation in one of two cancer susceptibility genes, BRCA1 and BRCA2. We searched for genes that have the potential to distinguish healthy BRCA1 and BRCA2 mutation carriers from noncarriers based on differences in expression profiling. Using expression microarrays, we compared gene expression of irradiated lymphocytes from BRCA1 and BRCA2 mutation carriers versus control...
Paper Details
Title
Determination of Molecular Markers for BRCA1 and BRCA2 Heterozygosity Using Gene Expression Profiling
Published Date
Feb 1, 2013
Journal
Volume
6
Issue
2
Pages
82 - 90
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