Evolving insights on how cytosine methylation affects protein–DNA binding

Volume: 14, Issue: 1, Pages: 61 - 73
Published: Jan 1, 2015
Abstract
Many anecdotal observations exist of a regulatory effect of DNA methylation on gene expression. However, in general, the underlying mechanisms of this effect are poorly understood. In this review, we summarize what is currently known about how this important, but mysterious, epigenetic mark impacts cellular functions. Cytosine methylation can abrogate or enhance interactions with DNA-binding proteins, or it may have no effect, depending on the...
Paper Details
Title
Evolving insights on how cytosine methylation affects protein–DNA binding
Published Date
Jan 1, 2015
Volume
14
Issue
1
Pages
61 - 73
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.