O-Arylmandelic acids as highly selective human PPAR α/γ agonists
Volume: 13, Issue: 19, Pages: 3185 - 3190
Published: Oct 1, 2003
Abstract
A new class of O-arylmandelic acid PPAR agonists show excellent anti-hyperglycemic efficacy in a db/db mouse model of DM2. These PPARalpha-weighted agonists do not show the typical PPARgamma associated side effects of BAT proliferation and cardiac hypertrophy in a rat tolerability...
Paper Details
Title
O-Arylmandelic acids as highly selective human PPAR α/γ agonists
Published Date
Oct 1, 2003
Volume
13
Issue
19
Pages
3185 - 3190
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