The microglial sensome revealed by direct RNA sequencing
Abstract
Microglia, the principal neuroimmune sentinels of the brain, continuously sense changes in their environment and respond to invading pathogens, toxins and cellular debris. Microglia exhibit plasticity and can assume neurotoxic or neuroprotective priming states that determine their responses to danger. We used direct RNA sequencing, without amplification or cDNA synthesis, to determine the quantitative transcriptomes of microglia of healthy adult...
Paper Details
Title
The microglial sensome revealed by direct RNA sequencing
Published Date
Dec 1, 2013
Journal
Volume
16
Issue
12
Pages
1896 - 1905
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