Charting a dynamic DNA methylation landscape of the human genome
Abstract
DNA methylation is a defining feature of mammalian cellular identity and is essential for normal development. Most cell types, except germ cells and pre-implantation embryos, display relatively stable DNA methylation patterns, with 70-80% of all CpGs being methylated. Despite recent advances, we still have a limited understanding of when, where and how many CpGs participate in genomic regulation. Here we report the in-depth analysis of 42...
Paper Details
Title
Charting a dynamic DNA methylation landscape of the human genome
Published Date
Aug 1, 2013
Journal
Volume
500
Issue
7463
Pages
477 - 481
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