RHD gene polymorphisms in alloimmunized RhD-negative individuals with high rate of racial admixture

The D-negative phenotype is the result of the total RHD gene deletion in almost all Caucasians, but it accounts for only about 20% in Africans and 70% in Asians. In Africans the RHDΨ that is one of the most important causes of the D-negative phenotype. We investigated the RHD polymorphisms in D-negative phenotype mixed Brazilians who have anti-D alloantibody.Blood samples from 130 individuals previously typed as D-negative were phenotyped again...