Autotransporter passenger proteins: virulence factors with common structural themes
Abstract
Autotransporter proteins are virulence factors associated with a wide variety of diseases caused by pathogenic Gram-negative bacteria, and they play a variety of roles in pathogenesis including disabling host defences and mediating colonization. Pertactin, a key component of the whooping cough vaccine, is an autotransporter protein. A large sub-family of the autotransporters carries a trypsin-like protease domain, but these enzymes have...
Paper Details
Title
Autotransporter passenger proteins: virulence factors with common structural themes
Published Date
Mar 9, 2010
Volume
88
Issue
5
Pages
451 - 458
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