Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest.
Abstract
Many chemotherapeutic agents have been used to treat pancreatic cancer without success. Apigenin, a naturally occurring flavonoid, has been shown to inhibit growth in some cancer cell lines but has not been studied in pancreatic cancer. We hypothesized that apigenin would inhibit pancreatic cancer cell growth in vitro. Apigenin caused both time- and concentration-dependent inhibition of DNA synthesis and cell proliferation in four pancreatic...
Paper Details
Title
Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest.
Published Date
Dec 29, 2006
Journal
Volume
5
Issue
1
Pages
76 - 76
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