Sodium-iodide symporter (NIS) gene expression in lymph-node metastases of papillary thyroid carcinomas
Abstract
To investigate the molecular mechanisms underlying the influence of alteration of iodine trapping on the prognosis of metastatic papillary thyroid carcinomas, focusing on the expression of the Na+/I(-) symporter (NIS).We evaluated the expression of the NIS gene in a series of 11 enlarged neck lymph-node metastases of papillary thyroid carcinomas, including four patients in whom an enlarged lymph node represented the first sign of the tumoral...
Paper Details
Title
Sodium-iodide symporter (NIS) gene expression in lymph-node metastases of papillary thyroid carcinomas
Published Date
Nov 1, 2000
Pages
623 - 627
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