The natural course of non-functioning pituitary macroadenomas

The natural history of non-functioning pituitary macroadenomas (NFMA) has not been completely elucidated. Therefore, we evaluated pituitary function, visual fields, and tumor size during long-term follow-up of non-operated patients with NFMA.Follow-up study.Twenty-eight patients (age 55 +/- 3 years) with NFMA, not operated after initial diagnosis, were included.Initial presentation was pituitary insufficiency in 44%, visual field defects in 14%,...