Peroxiredoxins in breast carcinoma.

Peroxiredoxins (Prxs) are a novel group of peroxidases containing high antioxidant efficiency and some of them having also effects on cell differentiation and apoptosis. The mammalian Prx family has six distinct members located in various subcellular locations, including peroxisomes and mitochondria, places where oxidative stress is most evident.We examined immunohistochemically a large set of samples from patients with breast carcinoma and...