Silica Nanoparticle Stabilization of Liquid Crystalline Lipid Dispersions: Impact on Enzymatic Digestion and Drug Solubilization

Volume: 12, Issue: 1, Pages: 47 - 55
Published: Mar 10, 2015
Abstract
The high internal surface area and drug solubilizing capacity of liquid crystal lipids makes them promising oral drug delivery systems. Pluronic F127 is typically used to disperse highly viscous cubic liquid crystal lipids into cubosomes; however, such copolymers alter the internal structure and provide little control over enzymatic digestion. This study aimed to use hydrophilic silica nanoparticles to stabilize glyceryl monooleate (GMO)...
Paper Details
Title
Silica Nanoparticle Stabilization of Liquid Crystalline Lipid Dispersions: Impact on Enzymatic Digestion and Drug Solubilization
Published Date
Mar 10, 2015
Volume
12
Issue
1
Pages
47 - 55
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