Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer
Abstract
High-grade serous ovarian carcinoma (HGS-OvCa) has the lowest survival rate among all gynecologic cancers and is hallmarked by a high degree of heterogeneity. The Cancer Genome Atlas network has described a gene expression-based molecular classification of HGS-OvCa into Differentiated, Mesenchymal, Immunoreactive and Proliferative subtypes. However, the biological underpinnings and regulatory mechanisms underlying the distinct molecular subtypes...
Paper Details
Title
Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer
Published Date
Nov 4, 2015
Journal
Volume
5
Issue
1
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