Psychometric considerations in using error-related brain activity as a biomarker in psychotic disorders.

Psychotic disorders are characterized by profoundly blunted neural responses to errors, as indicated by reductions in two event-related potential (ERP) components: the error-related negativity (ERN) and error positivity (Pe). The potential utility of the ERN and Pe as biomarkers for psychotic disorders is currently limited, however, by an incomplete understanding of their psychometric properties. To address this gap in the literature, we...