Review paper
The cytokine TNF-alpha. Genetics and suitability for prenatal risks assessment.
Abstract
The tumor necrosis factor (TNF-alpha) is a cytokine known as a mediator of inflammation and immunity. The genes coding the tumor necrosis factors alpha and beta are considered part of class III major histocompatability complex. The 2 involved genes have been mapped to chromosome 6. Certain mutations in the TNF-alpha gene are believed to be causative for increased production of the cytokine. In this respect, the most common variant is the TNF2...
Paper Details
Title
The cytokine TNF-alpha. Genetics and suitability for prenatal risks assessment.
Published Date
Feb 1, 2004
Journal
Volume
25
Issue
2
Pages
135 - 40
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Notes
History