Synthesis and in vitro evaluation of amphiphilic peptides and their nanostructured conjugates.

Breast cancer is the second leading cancer type among people of advanced countries. Various methods have been used for cancer treatment such as chemotherapy and radiotherapy. In the present study we have designed and synthesized a new group of drug delivery systems (DDS) containing a new class of Cell Penetrating Peptides (CPPs) named Peptide Amphiphiles (PAs).Two PAs and anionic peptides were synthesized using solid phase peptide synthesis...