The fibrillin-1 gene: unlocking new therapeutic pathways in cardiovascular disease

Heart5.70
Volume: 99, Issue: 2, Pages: 83 - 90
Published: Sep 2, 2012
Abstract
The dramatic reductions in DNA sequencing costs allow us to delve deeper into the genomic alterations that increase susceptibility to many polygenic cardiovascular diseases. One such condition is an abnormal proximal aorta. Until recently, many believed that dilated, distorted or dissected proximal aortas might represent a forme fruste of Marfan syndrome or a continuum of aortopathy. Although an FBN-1 mutation does not guarantee the...
Paper Details
Title
The fibrillin-1 gene: unlocking new therapeutic pathways in cardiovascular disease
Published Date
Sep 2, 2012
Journal
Volume
99
Issue
2
Pages
83 - 90
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