Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
Volume: 124, Issue: 2, Pages: 499 - 508
Published: Jan 27, 2014
Abstract
Sodium-glucose cotransporter 2 (SGLT2) inhibitors lower glycemia by enhancing urinary glucose excretion. The physiologic response to pharmacologically induced acute or chronic glycosuria has not been investigated in human diabetes.We evaluated 66 patients with type 2 diabetes (62 ± 7 years, BMI = 31.6 ± 4.6 kg/m(2), HbA1c = 55 ± 8 mmol/mol, mean ± SD) at baseline, after a single dose, and following 4-week treatment with empagliflozin (25 mg). At...
Paper Details
Title
Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
Published Date
Jan 27, 2014
Volume
124
Issue
2
Pages
499 - 508
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