Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb
Abstract
A defect in transcapillary transport of insulin in skeletal muscle and adipose tissue has been proposed to play a role in the insulin resistance that leads to type 2 diabetes, yet the mechanism of insulin transfer across the capillary endothelium from plasma to interstitium continues to be debated. This study examined in vivo the interstitial appearance of insulin in hindlimb using the fatty acid acylated insulin analog LysB29-tetradecanoyl...
Paper Details
Title
Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb
Published Date
Mar 1, 2002
Journal
Volume
51
Issue
3
Pages
574 - 582
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