Inflammasome-Independent Regulation of IL-1-Family Cytokines
Abstract
Induction, production, and release of proinflammatory cytokines are essential steps to establish an effective host defense. Cytokines of the interleukin-1 (IL-1) family induce inflammation and regulate T lymphocyte responses while also displaying homeostatic and metabolic activities. With the exception of the IL-1 receptor antagonist, all IL-1 family cytokines lack a signal peptide and require proteolytic processing into an active molecule. One...
Paper Details
Title
Inflammasome-Independent Regulation of IL-1-Family Cytokines
Published Date
Mar 21, 2015
Journal
Volume
33
Issue
1
Pages
49 - 77
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