Review paper
Origins of Specificity in Protein-DNA Recognition
Abstract
Specific interactions between proteins and DNA are fundamental to many biological processes. In this review, we provide a revised view of protein-DNA interactions that emphasizes the importance of the three-dimensional structures of both macromolecules. We divide protein-DNA interactions into two categories: those when the protein recognizes the unique chemical signatures of the DNA bases (base readout) and those when the protein recognizes a...
Paper Details
Title
Origins of Specificity in Protein-DNA Recognition
Published Date
Jun 7, 2010
Volume
79
Issue
1
Pages
233 - 269
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