Diet-induced increase in plasma oxidized LDL promotes early fibrosis in a renal porcine auto-transplantation model
Abstract
In kidney transplantation, the prevalence of hypercholesterolemia as a co-morbidity factor known to affect graft function, is rising due to the increased number of older donors in response to organ shortage as well as to the hyperlipidemic effects of immunosuppressors in recipient. This study aimed to characterize the effects of hypercholesterolemia on renal graft outcome, investigating the role of oxidized low-density lipoprotein (OxLDL). In...
Paper Details
Title
Diet-induced increase in plasma oxidized LDL promotes early fibrosis in a renal porcine auto-transplantation model
Published Date
Mar 22, 2014
Volume
12
Issue
1
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