Lin28 Enhances Tissue Repair by Reprogramming Cellular Metabolism
Abstract
Summary null Regeneration capacity declines with age, but why juvenile organisms show enhanced tissue repair remains unexplained. null Lin28a , a highly conserved RNA-binding protein expressed during embryogenesis, plays roles in development, pluripotency, and metabolism. To determine whether null Lin28a null might influence tissue repair in adults, we engineered the reactivation of null Lin28a null expression in several models of tissue injury....
Paper Details
Title
Lin28 Enhances Tissue Repair by Reprogramming Cellular Metabolism
Published Date
Nov 7, 2013
Journal
Volume
155
Issue
4
Pages
778 - 792
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