Platelet deposition in a capillary perfusion model: quantitative and morphological aspects

The capillary perfusion model according to Cazenave and co-workers was characterized by investigatingium labelling of human platelets and scanning electron microscopy (SEM). Compared with uncoated polyethylene, platelet deposition was increased after precoating with purified human von Willebrand factor, fibrinogen or fibronectin, and decreased by preadsorbed immunoglobulin G, albumin or whole plasma. Platelet aggregates were observed on...