Time-trends in health technology assessments: An analysis of developments in composition of international health technology assessments from 1989 to 2002

Health Technology Assessment (HTA) as a method for producing evidence in the health-care sector has been used for more than 25 years but has grown in extent during the past years. The objective of this study is to explore a possible evolution in these HTAs, in type of assessed technologies, in type of assessors, and in its methods.A structured literature review was conducted of 433 HTA reports from the period 1989 to 2002 by eleven leading HTA...