Aging, Cellular Senescence, and Cancer
Abstract
For most species, aging promotes a host of degenerative pathologies that are characterized by debilitating losses of tissue or cellular function. However, especially among vertebrates, aging also promotes hyperplastic pathologies, the most deadly of which is cancer. In contrast to the loss of function that characterizes degenerating cells and tissues, malignant (cancerous) cells must acquire new (albeit aberrant) functions that allow them to...
Paper Details
Title
Aging, Cellular Senescence, and Cancer
Published Date
Feb 10, 2013
Journal
Volume
75
Issue
1
Pages
685 - 705
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