Abundance of IgG4+ Plasma Cells in Isolated Reactive Lymphadenopathy Is No Indication of IgG4-Related Disease

IgG4-related disease is a recently recognized condition that can be associated with lymphadenopathy, with several histologic patterns and increased absolute number and ratio of immunoglobulin G4 (IgG4)-positive plasma cells. However, these findings are considered to be not exclusively specific for IgG4-related disease.The occurrence of the histologic patterns reported in patients with isolated lymphadenopathy was studied and correlated with the...