High Efficiency Activation of L-Type Ca2+Current by 5-HT in Human Atrial Myocytes
Abstract
In human atrial myocytes, serotonin rather than sympathetic, stimulation is more frequently associated with atrial fibrillation. So does the arrhythmogenic effect of serotonin result from the mechanism of action of the receptor or the context of its action upon cardiac myocytes? The capacity of agonists to produce cAMP followed the sequence 5-HT < Iso < Forskolin to increase ICaL with 5-HT = Iso = Forskolin. The simultaneous application of...
Paper Details
Title
High Efficiency Activation of L-Type Ca2+Current by 5-HT in Human Atrial Myocytes
Published Date
Jan 1, 2004
Journal
Volume
10
Issue
5-6
Pages
159 - 165
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